Table 1.
kDaa | % cov. | Copies from gel densityb | Proposed function | Expected copiesc | SC/MW | Terminal residues unsampled (N,C) | |
---|---|---|---|---|---|---|---|
gp37 | 174.9 | 65 | 4±2 | IVP-D | 4 | 4.3 | 0,0 |
gp55 | 73.2 | 86 | 12±6 | Side fiber | 18 | 11.2 | 6,0 |
gp36 | 63.8 | 70 | 6±3 | IVP-C | 8 | 7.8 | 0,0 |
gp51 | 63.6 | 68 | 9±4 | Portal | 12 | 6.2 | 0,0 |
gp40 | 44.4 | 78 | 7±3 | Tube B (C ter) | 6 | 3.6 | 7,5 |
gp42 | 41.4 | 63 | 23±15d | 4.0 | 38,5 | ||
gp44 | 35.0 | 59 | n.d.d | Tube B (N ter) | 6 | 0.9 | 5,0 |
gp48 | 35.2 | 97 | 415e | Major capsid | 415 | 53.5 | 0,0 |
gp46 | 28.8 | 49 | 15±7 | Tube A | 12 | 2.5 | 21,4 |
gp47 | 17.6 | 86 | 275±140f | 14.6 | 0,0 | ||
gp43 | 19.1 | 75 | n.d.f | 5.6 | 1,4 | ||
gp38 | 14.8 | 79 | <17g | IVP-B | 12 | 9.4 | 43,0 |
Molecular weight adjusted for loss of N terminal methionine confirmed by semitryptic fragment observed for gp37, gp36, gp51, and gp43. Presence of N-terminal methionine was confirmed for gp48 and gp47.
Number of polypeptides per virion with estimated 95% confidence interval.
From the precedent in T7 (Molineux, 2006; Guo et al., 2013).
Gp42 and gp44 comigrate; the sum is given.
Peak area of gp48 was assumed to correspond to 415 copies for calibration purposes.
Gp47 and gp43 comigrate; the sum is given.
There was no Coomassie-staining peak observed in the gel profile within the slice exhibiting gp38 tryptic fragments. The total area above our best estimate of the baseline across the slice was used to project the indicated maximum copy number.