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Physico-chemical characterization of PBNB and effect of US exposure. (A) Bar diagrams of change in hydrodynamic diameter of PBNBs and NBs after US exposure; (B) Comparison in average particle size variation obtained from three independent experiments; (C) Zeta potential distribution; anhydrous state morphology of (D) PBNB and (E) pro-bexarotene-NPs; (F) XRD patterns of pro-bexarotene-NPs, PBNB and PBNB+US.
