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. 2016 Apr 4;11(4):e0152675. doi: 10.1371/journal.pone.0152675

Table 4. Top 10 enrichment KEGG pathways in the DGEs.

Pathway DEGs with pathway annotation (1157) a All genes with pathway annotation (18965)b P-value
1 Complement and coagulation cascades 31 (2.68%) 206 (1.09%) 2.910213e-06
2 Amoebiasis 83 (7.17%) 938 (4.95%) 0.0003921369
3 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 20 (1.73%) 145 (0.76%) 0.0005192677
4 ECM–receptor interaction 66 (5.7%) 720 (3.8%) 0.0006085478
5 Glycerolipid metabolism 14(1.21%) 89(0.47%) 0.0009503658
6 Metabolism of xenobiotics by cytochrome P450 15 (1.3%) 117 (0.62%) 0.005011024
7 Phagosome 34 (2.94%) 366 (1.93%) 0.009756936
8 Protein digestion and absorption 60 (5.19%) 729 (3.84%) 0.01112557
9 Drug metabolism—cytochrome P450 12 (1.04%) 94 (0.5%) 0.01174199
10 Circadian rhythm—mammal 6 (0.52%) 36 (0.19%) 0.02055234

a. The number of differentially expressed genes with pathway annotation.

b. The number of genes in the entire yak genome with pathway annotation.