Table 4. Major effects of UA and salt intake and their interaction.

	Men					Women
	UA, mmol/L		Salt intake, gram		Interaction	UA, mmol/L		Salt intake, gram		Interaction
	PR	P value	PR	P value	P value	PR	P value	PR	P value	P value
Age-adjusted simple model
Major effects without interaction item
Hypertension as dependent variable	1.031	0.004	1.093	0.002	–	1.031	0.004	1.115	< 0.001	–
mTCR as dependent variable	1.024	0.012	1.091	0.001	–	1.028	0.008	1.111	< 0.001	–
Major effects with interaction item
Hypertension as dependent variable	1.045	0.001	1.004	< 0.001	0.024	1.055	0.005	1.013	0.120	0.132
mTCR as dependent variable	1.039	0.002	1.004	< 0.001	0.019	1.075	< 0.001	1.022	0.002	0.010
Multivariable model
Major effects without interaction item
Hypertension as dependent variable*	1.007	0.333	1.067	0.075	–	0.999	0.912	1.107	< 0.001	–
mTCR as dependent variable**	1.024	0.015	1.096	0.014	–	1.021	0.032	1.114	< 0.001	–
Major effects with interaction item
Hypertension as dependent variable*	1.016	0.242	1.002	0.025	0.129	1.021	0.064	1.013	0.103	0.146
mTCR as dependent variable**	1.034	0.009	1.003	0.004	0.057	1.068	< 0.001	1.023	< 0.001	0.010

UA and salt intake as major effects were included in age-adjusted simple model with interaction item or not. UA level was categorized from its P₂₅ with a step of 20 mmol/L. Salt intake daily was categorized from 5 g with a step of 5 g in major effect-based model, however, defined as a continuous variable with a unit of gram in interaction item-based model.

*Adjusted for age, occupation, smoking (only for men), alcohol intake (only for men), BMI, plasma Cr, TC, fasting glucose, and antihypertensive treatment.

**Adjusted for age, occupation, and antihypertensive treatment.–Not applicable. mTCR: moderate-or-high total cardiovascular risk.