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. 2016 Mar 11;14(3):57. doi: 10.3390/md14030057
MNPs Marine natural products
FDA United States Food and Drug Administration
EMA European Medicines Agency
OIDD The Lilly Open Innovation Drug Discovery Program
TZD Thiazolidinon-2-yl
THP Tetrahydropyran
JAK Janus kinase
STATs Signal transducers and activators of transcription
VEGF Vascular endothelial growth factor
FLT3 Fms-like tyrosine kinase 3
RTK Receptor tyrosine kinase
RAS Rat sarcoma viral oncogene homolog
PI3K Phosphatidylinositol-4,5-biphopshate 3-kinase
Ephrin Eph receptor interacting protein
ABL1 Abelson murine leukemia viral oncogene homolog 1
CML Chronic myeloid leukemia
bFGF Basic fibroblast growth factor
TIE Tyrosine kinases with immunoglobulin-like and EGF-like domains
VEGFRs Vascular endothelial growth factor receptors
Grb2 Growth factor receptor-bound protein 2
EGF Epidermal growth factor
Ang Angiopoietin
GSK3-β Glycogen synthase kinase-3-beta
PLK Polo-like kinase
SAR Structure-activity relationship
ECFCs Endothelial colony-forming cells
ADSCs Human adipose-derived stem cells
cLogP Calculated logarithm of partition coefficient
HBD Hydrogen bond donor
HBA Hydrogen bond acceptor