Table 2.

Unconditional Analyses

Estimated mean scores at age 10 and change per year for each ABC-C subscale and VABS age equivalent for males and females with FXS.

Males	Mean Score at age 10			Change in Score Per Year (Slope)
	Estimate	95% CI		Estimate	95% CI		p-value	Effect Size
I. Irritability/ Agitation	10.00	7.92,	12.08	−0.32	−0.54,	−0.10	0.00	−0.55
II. Lethargy/Social Withdrawal	5.60	4.04	7.16	0.10	−0.07,	0.27	0.24	0.25
III. Stereotypic Behavior	4.86	3.69,	6.03	−0.11	−0.25,	0.03	0.11	−0.50
IV. Hyperactivity Noncompliance	15.16	12.95,	17.36	−0.61	−0.82,	−0.39	0.00	−2.74
V. Inappropriate Speech	4.30	3.51,	5.09	−0.01	−0.10,	0.09	0.92	−0.03
VABS Age Equivalent	4.78	4.26,	5.30	0.26	0.19,	0.33	< 0.001	3.04
Females	Mean Score at age 10			Change in Score Per Year (Slope)
	Estimate	95% CI		Estimate	95% CI		p-value	Effect Size
I. Irritability/ Agitation	5.97	4.02,	7.92	−0.25	−0.45,	−0.05	0.02	−0.44
II. Lethargy/Social Withdrawal	3.97	2.69,	5.24	0.03	−0.13,	0.19	0.71	0.07
III. Stereotypic Behavior	1.47	0.88,	2.07	−0.06	−0.12,	0.01	0.10	−0.25
IV. Hyperactivity Noncompliance	5.90	4.14,	7.66	−0.28	−0.42,	−0.14	0.00	−1.26
V. Inappropriate Speech	1.67	1.08,	2.27	−0.05	−0.11,	0.01	0.10	−0.26
VABS Age Equivalent	7.65	6.68,	8.61	0.49	0.36,	0.62	< 0.001	5.82