Table 1.
Circadian rhythm characteristics of circulating plasma lipid components in different age groups
Variable | RhythmometricSummary | ||||||
---|---|---|---|---|---|---|---|
Group | k | PR | P | MESOR ± SE | Amplitude (95 % CI) | Acrophase (95 % CI) | |
T-C | A | 42 | 81.2 | <0.001 | 170.4 ± 2.0 | 24.8 (22.1–27.6) | –244° (–236°,–252°) |
B | 60 | 81.0 | <0.001 | 170.2 ± 1.5 | 21.5 (19.6,23.4) | –267° (–261°,–274°) | |
C | 35 | 70.3 | <0.001 | 166.9 ± 1.3 | 16.4 (13.6–19.2) | –245° (–232°,–260°) | |
D | 25 | 82.0 | <0.001 | 165.5 ± 1.5 | 22.7 (20.2,25.2) | –221° (–213°,–228°) | |
HDL–C | A | 42 | 77.4 | <0.001 | 41.6 ± 0.7 | 12.6 (11.1–14.0) | –242° (–235°,–250°) |
B | 60 | 77.9 | <0.001 | 47.9 ± 0.6 | 13.1 (12.1–14.1) | –253° (–247°,–260°) | |
C | 35 | 80.7 | <0.001 | 46.3 ± 0.7 | 13.6 (12.0–15.2) | –245 (–239°,–253°) | |
D | 25 | 80.8 | <0.001 | 38.6 ± 1.0 | 10.4 (8.2–12.6) | –221° (–213°,–233°) | |
PL | A | 42 | 87.4 | <0.001 | 103.8 ± 1.3 | 22.5 (20.0–25.0) | –226° (–217°,–235°) |
B | 60 | 87.2 | <0.001 | 126.6 ± 1.5 | 25.5 (22.4–28.7) | –216° (–207°,–227°) | |
C | 35 | 83.1 | <0.001 | 125.7 ± 1.9 | 27.1 (22.9–31.3) | –232° (–222°,–243°) | |
D | 25 | 76.0 | 0.016 | 120.6 ± 2.5 | 8.7 (2.0–15.4) | –298° (–230°,–333°) | |
TL | A | 42 | 86.8 | <0.001 | 386.0 ± 7.4 | 75.1 (63.5–86.6) | –257° (–246°,–269°) |
B | 60 | 81.2 | <0.001 | 524.3 ± 9.3 | 75.1 (65.1–85.1) | –258° (–247°,–269°) | |
C | 35 | 71.0 | <0.001 | 505.9 ± 6.9 | 50.5 (40.4–60.7) | –242° (–225°,–260°) | |
D | 25 | 71.0 | =0.002 | 494.9 ± 12.8 | 29.0 (14.4–43.7) | –122° (–90°,–149°) |
Groups A: 7–20 years; B: 21–40 years; C: 41–60 years; D: 61–75 years
T-C total cholesterol, HDL-C high-density lipoprotein cholesterol, PL phospholipids, TL total lipids, k number of participants, PR percent rhythm–average proportion of variance accounted for by fit of 24-h cosine curve to individual data series, P p value from zero-amplitude (no-rhythm) test, M MESOR–a chronome-adjusted mean value, Amplitude circadian amplitude–measure of half the extent of predictable change within a day, Ø acrophase–measure of the timing of overall high recurring each day–expressed in (negative) degrees with 360° ≡ 24 h and 0° = 00:00, SE standard error, 95 % CI 95 % confidence interval