Table 2.

Interpretation and considered values of the parameters

Parameter	Description	Value	References
${\mathit{\beta }}_S$	Growth rate of sensitive bacteria	0.8 day−1	Mondragón et al. (2014)
$(1-c){\mathit{\beta }}_S,0<c<1$	Growth rate of resistant bacteria	0.4–0.1 day−1	Mondragón et al. (2014)-hypothesis
$k$	Growth rate of immune cells	0.6 day−1	Pugliese and Gandolfi (2008)
$\mathit{\eta }$	Rate of bacteria destroyed by immune cells	0.3 day−1	Pugliese and Gandolfi (2008)
$\mathit{\omega }$	Rate to the amount of present bacteria of carrying capacity of immune cells	1	Hypothesis
$T$	Carrying capacity of bacteria	109 bacteria	Alavez et al. (2006)
$\overline{{\mathit{\alpha }}_1}$	Mutation rate of INH	10−6 mut×gen	Coll (2009)
$\overline{{\mathit{\alpha }}_2}$	Mutation rate of PZA	0	Mondragón et al. (2014)
$\overline{d_1}$	Elimination rate of sensitive bacteria due INH	0.0039 day−1	Zhang (2009)
$\overline{d_2}$	Elimination rate of sensitive bacteria due PZA	0.0001625 day−1	Alavez et al. (2006)
${\mathit{\delta }}_1$	Daily dose of INH	5 mg/kg/day	Coll (2009)
${\mathit{\delta }}_2$	Daily dose of ZPA	35–20 mg/kg/day	Coll (2009)
${\mathit{\mu }}_1$	Uptake rate of INH	0.06 day−1	Esteva et al. (2011)
${\mathit{\mu }}_2$	Uptake rate of PZA	0.03 day−1	Esteva et al. (2011)

Datas are deduced from the literature

The values obtained from this table are that (i) in the first case, $A=0.260674$, $B=0.571428$ $\left(A<B\right)$ and so, $E_2=\left(0,0.5714,0.5714,1,\dots ,1\right)$ is LAS. (ii) in the second case, $A=0.334538$, $B=0.25$ $\left(A>B\right)$ and so, $E_3=\left(0.3337,0.0008,0.3345,1,1,\dots ,1\right)$ is LAS

Among the treatment regimen recommended by WHO includes isoniazid (INH) and pyrazinamide (PZA) for some bacterial infectious (such as Mycobacterium tuberculosis) (Coll 2009)