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. 2016 Apr 5;10:146. doi: 10.3389/fnins.2016.00146

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Copyright © 2016 Roy, Campbell, Bernier and Hillary.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The figure illustrates an example of a positively and negatively plastic sub-regional-pair. In this figure, session-1 and session-2 refers to two fMRI-scan sessions that are separated by finite duration of time; chronologically, session-2 occurs after session-1. Edges indicate a voxel from ROI-A is significantly correlated with a voxel from ROI-B. The red sub-regional-pair gains functional edges from session-1 to session-2 (hence positive plastic), while the blue sub-regional-pair shows decline in the number of functional edges (hence negative plastic). The binomial test based objective functional detects such plastic sub-regional-pairs.