Table 3.
HR of dying from ALS according to type of physical activity
| ALS cases | Adjusted HR (95 % CI)a | Adjusted HR (95 % CI)a including BMI | Adjusted HR (95 % CI)a including WHR | |
|---|---|---|---|---|
| Cambridge index of physical activity | ||||
| Inactive | 72 (32.9) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
| Moderately inactive | 80 (36.5) | 0.88 (0.63–1.22) | 0.86 (0.62–1.20) | 0.92 (0.64–1.34) |
| Moderately active | 38 (17.4) | 0.70 (0.46–1.05) | 0.68 (0.45–1.03) | 0.76 (0.48–1.20) |
| Active | 29 (13.2) | 0.67 (0.42–1.06) | 0.65 (0.41–1.04) | 0.67 (0.40–1.11) |
| p-trend | 0.042 | 0.032 | 0.084 | |
| Occupational activity | ||||
| Sedentary | 28 (35.4) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
| Standing | 34 (43.0) | 1.39 (0.83–2.35) | 1.39 (0.83–2.35) | 1.73 (0.97–3.09) |
| Manual/heavy manual | 17 (21.5) | 1.28 (0.67–2.44) | 1.28 (0.67–2.43) | 1.61 (0.80–3.24) |
| p-trend | 0.341 | 0.343 | 0.113 | |
| Household activity | ||||
| 1st quartile | 42 (20.0) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
| 2nd quartile | 69 (32.9) | 1.43 (0.97–2.11) | 1.43 (0.97–2.11) | 1.77 (1.11–2.78) |
| 3rd quartile | 42 (20.0) | 0.82 (0.52–1.27) | 0.81 (0.52–1.27) | 0.94 (0.57–1.56) |
| 4th quartile | 57 (27.1) | 1.11 (0.72–1.70) | 1.11 (0.73–1.71) | 1.25 (0.77–2.02) |
| p-trend | 0.649 | 0.662 | 0.795 | |
| Recreational activity | ||||
| 1st quartile | 46 (21.9) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
| 2nd quartile | 56 (26.7) | 1.06 (0.71–1.57) | 1.05 (0.70–1.55) | 1.07 (0.70–1.63) |
| 3rd quartile | 59 (28.1) | 1.15 (0.77–1.70) | 1.13 (0.76–1.67) | 0.93 (0.60–1.45) |
| 4th quartile | 49 (23.3) | 0.91 (0.60–1.39) | 0.89 (0.59–1.36) | 0.83 (0.53–1.31) |
| p-trend | 0.770 | 0.688 | 0.328 | |
| Practising sports | ||||
| No | 131 (29.8) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
| Below the median | 36 (16.4) | 0.85 (0.58–1.24) | 0.84 (0.57–1.23) | 0.82 (0.54–1.25) |
| Above the median | 52 (23.7) | 1.03 (0.74–1.44) | 1.01 (0.72–1.41) | 1.01 (0.70–1.45) |
| p-trend | 0.985 | 0.921 | 0.899 | |
| Potentially traumatic physical activity | ||||
| Never | 90 (41.1) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
| Ever | 129 (58.1) | 0.93 (0.69–1.26) | 0.92 (0.67–1.24) | 0.91 (0.65–1.26) |
| Vigorous physical activity | ||||
| None | 96 (60.4) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
| ≤2 h/week | 39 (24.5) | 1.16 (0.77–1.75) | 1.15 (0.77–1.74) | 1.05 (0.65–1.68) |
| >2 h/week | 24 (15.1) | 0.89 (0.55–1.43) | 0.89 (0.55–1.43) | 0.93 (0.55–1.57) |
| p-trend | 0.789 | 0.769 | 0.833 | |
aModel stratified by centre and age and adjusted for smoking status, highest level of education attained, and sex