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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Biotechnol Bioeng. 2015 Sep 3;113(2):414–423. doi: 10.1002/bit.25710

Table I.

Amino acid frequencies at sites 24 and 27 in entA homologs.

Amino Acid Site 24 Site 27
A 22% 6%
C 0% 0%
D 0% 0%
E 0% 2%
F 0% 5%
G 54% 0%
H 0% 0%
I 0% 21%
K 0% 15%
L 0% 0%
M 0% 0%
N 9% 2%
P 1% 0%
Q 1% 1%
R 0% 3%
S 14% 5%
T 0% 23%
V 0% 0%
W 0% 16%
Y 0% 0%

Natural homologs of entA (n = 138) were identified in the Pfam database. Amino acid frequencies at sites 24 and 27 were calculated. The impact of identical sequences was dampened by counting the square root of their occurrence.