Table 2.
Patient characteristics
| Factor |
Cirrhosis with acute decompensation from etiologies other than alcohol (n = 23) |
Alcoholic hepatitis (n = 25) |
P-value | ||
| n | Summary | n | Summary | ||
| Age (yr) | 14 | 53.8 ± 9.8 | 20 | 51.5 ± 10.4 | 0.511 |
| Male | 21 | 13 (61.9) | 23 | 10 (43.5) | 0.223 |
| Caucasian | 10 | 10 (100.0) | 19 | 16 (84.2) | 0.534 |
| AST | 23 | 40.0 (33.0, 75.0) | 25 | 138.0 (88.0, 161.0) | < 0.0012b |
| ALT | 23 | 21.0 (15.0, 30.0) | 25 | 51.0 (42.0, 71.0) | < 0.0012b |
| Bilirubin | 23 | 3.8 (1.4, 6.0) | 25 | 9.4 (6.8, 21.7) | 0.0052b |
| Albumin | 23 | 2.8 ± 0.66 | 25 | 2.8 ± 0.68 | 0.861 |
| INR | 23 | 1.5 ± 0.41 | 25 | 1.7 ± 0.59 | 0.161 |
| PT | 23 | 16.4 ± 4.5 | 25 | 19.1 ± 6.1 | 0.0951 |
| Creatinine | 23 | 0.94 (0.74, 1.5) | 25 | 0.72 (0.57, 1.04) | 0.0622 |
| MELD score | 23 | 16.4 ± 8.8 | 25 | 20.5 ± 10.0 | 0.141 |
| Maddrey's score | 16 | 22.2 (16.0, 37.0) | 17 | 43.5 (34.0, 60.6) | 0.0282a |
| Ascites | 23 | 25 | 0.142 | ||
| None | 9 (39.1) | 14 (56.0) | |||
| Small | 4 (17.4) | 6 (24.0) | |||
| Large | 9 (39.1) | 4 (16.0) | |||
| Severe | 1 (4.3) | 1 (4.0) | |||
| HE | 23 | 25 | 0.942 | ||
| None | 2 (8.7) | 6 (24.0) | |||
| Mild | 12 (52.2) | 7 (28.0) | |||
| Severe | 9 (39.1) | 12 (48.0) | |||
| Steroids | 23 | 2 (8.7) | 25 | 13 (52.0) | 0.0013b |
| Trental | 23 | 3 (13.0) | 25 | 9 (36.0) | 0.0673 |
| OLT | 23 | 2 (8.7) | 25 | 1 (4.0) | 0.604 |
| Deceased | 23 | 6 (26.1) | 25 | 8 (32.0) | 0.653 |
P-values were calculated using the test corresponding to superscript characters:
1
ANOVA;
2
Kruskal-Wallis test;
3
Pearson’s χ2 test;
4
Fisher’s exact test.
a
P < 0.05 and
b
P < 0.01. AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; MELD: Model for end-stage liver disease; OLT: Orthotopic liver transplantation; PT: Prothrombin time; INR: International normalized ratio; HE: Hepatic encephalopathy.