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Terminal region genome sequences that are involved in 3′–5′ long distance RNA–RNA interactions. The three pairs of inverted complementary sequences that may mediate genome cyclization and allow the RdRp to reach the 3′ SL initiation site for RNA synthesis are enlarged. Abbreviations: dumbbell, DB; open reading frame, sHP-3' ORF; small hairpin 3'-stem-loop, sHP-3'-SL; stem Loop, SL; Y-shape stem-loop, SLA; untranslated region, UTR.
