Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jun 22;35(13):1671–1678. doi: 10.1038/onc.2015.231

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016 Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

PMC Copyright notice

MYC occupies the ITGA1 promoter. (a) ChIP assay with an anti-human c-Myc-specific antibody or with a Pol-II antibody was performed in HT29 cells and real-time quantitative PCR (qPCR) amplification products were migrated on gel. Mock immunoprecipitation with mouse anti-IgG was performed as negative control. (b) Enrichment of the ITGA1 promoter region containing the MYC response elements was calculated by PCR quantification relative to the amount of control chromatin without response element for MYC. (c) Enrichment for the CCND1 promoter containing one complete EBOX response element was used as a positive control. Results represent the mean of three independent experiments, with qPCR performed in triplicate. *P<0.05, **P<0.01.