Figure 1. Sirt6 protein expression is lower in human carotid endarterectomy specimens than in normal carotids.

(A) The Sirt6 protein level in human atherosclerotic plaques and normal carotids from controls was analyzed in representative western blot. MMP9 acts as a positive control. (B) Statistical analysis of the Sirt6 protein level relative to β-Actin in normal carotids (n = 7) and atherosclerotic plaques (n = 14) is shown. Each symbol represents a measurement from a single sample. Student’s t test was applied to calculate the P value. (*P < 0.05).