Table 4. Relationship of fecal Synergistetes and IL-6 serum levels with anti-PC and total IgM and IgG antibodies.
Synergistetes |
IL-6 |
|||
---|---|---|---|---|
HC | SLE | HC | SLE | |
IgM: | ||||
anti-PC | r = 0.404 | r = 0.624* | r = −0.004 | r = −0.473 |
p = 0.062 | p = 0.002 | p = 0.986 | p = 0.030 | |
total | r = 0.101 | r = 0.824* | r = 0.081 | r = −0.642* |
p = 0.662 | p < 0.001 | p = 0.729 | p = 0.002 | |
IgG: | ||||
anti-PC | r = −0.156 | r = 0.239 | r = −0.049 | r = −0.038 |
p = 0.523 | p = 0.286 | p = 0.842 | p = 0.286 | |
total | r = −0.301 | r = −0.078 | r = 0.133 | r = 0.332 |
p = 0.211 | p = 0.737 | p = 0.586 | p = 0.142 | |
IgM/IgG ratio: | ||||
anti-PC | r = 0.670 | r = 0.495* | r = −0.005 | r = −0.488 |
p = 0.002 | p = 0.023 | p = 0.983 | p = 0.025 | |
total | r = 0.496 | r = 0.597* | r = −0.082 | r = −0.610* |
p = 0.031 | p = 0.004 | p = 0.737 | p = 0.003 |
Correlation analyses were evaluated by Spearman test and confirmed by multivariate linear regression analyses adjusted by weight, BMI and blood lipids (*p < 0.05, R2 > 0.6).