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. 2016 Feb 20;7(5):538–545. doi: 10.7150/jca.14206

Table 3.

Relationship between tumor- and host-related characteristics and disease-free survival in 255 patients with endometrial cancer

Variable Univariate Multivariate
HR (95% CI) P-value HR (95% CI) P-value
Age (years) (≤ 56 vs. > 56) 3.59 (1.39, 9.29) 0.0085
Histology (endometrioid vs. others) 7.81 (3.05, 19.97) < 0.0001
Histologic grade (G1 vs. G2-G3) 10.81 (2.52, 46.41) 0.0014 9.57 (2.08, 44.01) 0.0037
FIGO stage (I-II vs. III-IV) 15.09 (6.03, 37.78) < 0.0001 8.14 (3.14, 21.11) < 0.0001
LVSI (absent vs. present) 8.29 (3.43, 20.03) < 0.0001
CA-125 (unit/mL) (≤ 48.1 vs. > 48.1) 5.54 (2.20, 13.97) < 0.0001
Albumin (g/dL) (≤ 4.4 vs. > 4.4) 0.21 (0.06, 0.73) 0.0138
WBC (per µL) (≤ 5410 vs. > 5410) 5.86 (0.79, 43.31) 0.0848
ANC (per µL) (≤ 3665.1 vs. > 3665.1) 3.01 (1.01, 8.94) 0.0478
ALC (per µL) (≤1526.9 vs. >1526.9) 0.25 (0.10, 0.60) 0.0019
AMC (per µL) (≤ 528.4 vs. > 528.4) 4.83 (2.01, 11.64) < 0.0001
Hemoglobin (g/dL) (≤11.7 vs. >11.7) 0.31 (0.13, 0.74) 0.0079
MCV (fL) (≤ 90 vs. > 90) 3.16 (1.26, 7.91) 0.0139
Platelet (x 103/µL) (≤204 vs. >204) 0.34 (0.13, 0.89) 0.0282
NLR (≤ 2.44 vs. > 2.44) 3.68 (1.55, 8.76) 0.0032
PLR (≤ 190.78 vs. > 190.78) 3.08 (1.30, 7.32) 0.0108
LMR (≤ 3.28 vs. > 3.28) 0.10 (0.04, 0.25) < 0.0001 0.10 (0.03, 0.32) < 0.0001

HRs were obtained from Cox's proportional hazard model.

HR, hazard ratio; CI, confidence interval; FIGO, International Federation of Gynecology and Obstetrics; LVSI, lymphovascular space invasion;CA-125, cancer antigen 125; WBC, white blood cell; ANC, absolute neutrophil count; ALC, absolute lymphocyte count; AMC, absolute monocyte count; MCV, mean corpuscular volume; NLR, neutrophil-lymphocyte ratio; PLR, platelet-lymphocyte ratio; LMR, lymphocyte-monocyte ratio