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. 2016 Feb 20;7(5):538–545. doi: 10.7150/jca.14206

Table 4.

Relationship between tumor- and host-related characteristics and overall survival in 255 patients with endometrial cancer

Variable Univariate Multivariate
HR (95% CI) P-value HR (95% CI) P-value
Age (years) (≤ 56 vs. > 56) 2.55 (0.85, 7.67) 0.0960
Histology (endometrioid vs. others) 12.868 (4.13, 40.02) < 0.0001
Histologic grade (G1 vs. G2-G3) 69.88 (0.94, 5173.32) 0.0531
FIGO stage (I-II vs. III-IV) 45.27 (10.00, 204.82) <0.0001 18.67 (4.08, 85.50) < 0.0001
LVSI (absent vs. present) 16.86 (4.70, 60.49) < 0.0001
CA-125 (unit/mL) (≤ 48.1 vs. > 48.1) 6.76 (2.23, 20.51) < 0.0001
Albumin (g/dL) (≤ 4.4 vs. > 4.4) 0.22 (0.05, 0.97) 0.0460
WBC (per µL) (≤ 5410 vs. > 5410) 3.52 (0.46, 27.04) 0.2260
ANC (per µL) (≤ 3665.1 vs. > 3665.1) 2.47(0.69, 8.85) 0.1663
ALC (per µL) (≤1526.9 vs. >1526.9) 0.26 (0.09,0.74) 0.0117
AMC (per µL) (≤ 528.4 vs. > 528.4) 4.86 (1.65, 13.32) 0.0042
Hemoglobin (g/dL) (≤11.7 vs. >11.7) 0.14 (0.04, 0.44) < 0.0001
MCV (fL) (≤ 90 vs. > 90) 3.01 (0.99, 9.13) 0.0513
Platelet (x 103/µL) (≤204 vs. >204) 0.32 (0.09, 1.07) 0.0638
NLR (≤ 2.44 vs. > 2.44) 3.47 (1.20, 10.05) 0.0217
PLR (≤ 190.78 vs. > 190.78) 2.89 (1.00, 8.38) 0.0497
LMR (≤ 3.28 vs. > 3.28) 0.02 (0.01, 0.55) < 0.0001 0.07 (0.02, 0.24) < 0.0001

HRs were obtained from Cox's proportional hazard model.

HR, hazard ratio; CI, confidence interval; FIGO, International Federation of Gynecology and Obstetrics; LVSI, lymphovascular space invasion;CA-125, cancer antigen 125; WBC, white blood cell; ANC, absolute neutrophil count; ALC, absolute lymphocyte count; AMC, absolute monocyte count; NLR, neutrophil-lymphocyte ratio; PLR, platelet-lymphocyte ratio; LMR, lymphocyte-monocyte ratio