Skip to main content
. 2016 Mar 18;7(5):576–586. doi: 10.7150/jca.13117

Figure 4.

Figure 4

The inhibitory effects of the specific siRNAs of lncRNA Z38 on breast cancer cell MDA-MB-231. (A) Images showing the effects of siRNAs on cell apoptosis, assayed by TUNEL assays. (B) Images of the colony formation in agarose of MDA-MB-231 after transfection with Z38 siRNAs. (C) Histogram showing the relative colony formation. (D) Images showing the effects of siRNAs on cell apoptosis. Cells were transiently co-transfected using siRNAs and plasmid pEGFP-C1-Z38(S). (E) Semi-quantitative PCR measuring Z38 expression level of MDA-MB-231 cells after transfection with siRNAs. (F) Image showing the influence of Z38 siRNAs on tumor growth, assayed by intratumoral injection. (G) Histogram showing the difference of tumor weight, assayed by intratumoral injection. * (p < 0.05) when compared with siRNA-1; # (P < 0.05) when compared with siRNA-2.