Table 1.
Results of univariate and multivariate analyses for ESCC overall survival (n = 180).
| Factors | P-value. | HR | 95.0% CI for HR | |
|---|---|---|---|---|
| Univariate analyses | Lower | Upper | ||
| Age (≤65 vs. >65 years) | 0.251 | 0.766 | 0.487 | 1.207 |
| Gender (male vs. female) | 0.549 | 0.789 | 0.364 | 1.712 |
| Smoking | 0.663 | 1.152 | 0.609 | 2.179 |
| Alcohol use | 0.871 | 0.950 | 0.544 | 1.766 |
| Tumor location | 0.977 | |||
| Middle esophagus vs. Lower esophagus | 0.845 | 0.861 | 0.191 | 3.888 |
| Upper esophagus vs. Lower esophagus | 0.962 | 1.012 | 0.625 | 1.638 |
| Tumor size | 0.502 | 1.047 | 0.916 | 1.196 |
| Differentiation | 0.972 | |||
| Grade 2 vs. Grade1 | 0.816 | 0.915 | 0.433 | 1.934 |
| Grade 3 vs. Grade1 | 0.890 | 0.964 | 0.576 | 1.613 |
| Stage (IIA-IIIA vs. IIIB-IIIC) | 0.444 | 1.221 | 0.732 | 2.036 |
| Venous or nerve invasion (no invasion vs. invasion) | 0.363 | 1.253 | 0.771 | 2.037 |
| EGFR (H-score > median vs. ≤ median) | 0.677 | 0.903 | 0.560 | 1.457 |
| c-Met (H-score > median vs. ≤ median) | 0.003 | 0.481 | 0.297 | 0.778 |
| HER2 (positive vs. negative) | 0.138 | 0.631 | 0.344 | 1.159 |
| Postoperative radiotherapy (no radiotherapy vs. radiotherapy ) | 0.155 | 0.698 | 0.426 | 1.145 |
| Postoperative chemotherapy (no chemotherapy vs. chemotherapy ) | 0.980 | 1.006 | 0.606 | 1.673 |
| Multivariate analysis | ||||
| EGFR (H-score > median vs. ≤ median ) | 0.421 | 0.831 | 0.530 | 1.304 |
| c-Met (H-score > median vs. ≤ median) | 0.001 | 0.459 | 0.287 | 0.733 |
| HER2 (positive vs. negative) | 0.205 | 0.685 | 0.381 | 1.230 |
| Postoperative radiotherapy (no radiotherapy vs. radiotherapy ) | 0.146 | 0.706 | 0.441 | 1.129 |
| Postoperative chemotherapy (no chemotherapy vs. chemotherapy ) | 0.940 | 0.982 | 0.614 | 1.157 |