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. 2016 Mar 18;7(5):600–607. doi: 10.7150/jca.13820

Figure 6.

Figure 6

Invasion assay of Tie2 overexpressed cells. (A) Invasion assay of Tie2 overexpressed cells. After crystal violet staining, the numbers of cells invading the pores are counted (×100 magnification). The numbers of penetrating oeTie2 cells are significantly lower than with Mock cells (*p < 0.05, Mann-Whitney U test). (B) Activation of cellular invasion by Tie2 antibody. The oeTie2 cells are treated with Tie2 antibody before the invasion assay. The numbers of oeTie2 cells invading the pores increase after treatment with Tie2 antibody (2 µg/ml) (B, SAS cells; C, Sa3 cells, ** p < 0.01).