. 2016 Mar 18;7(5):600–607. doi: 10.7150/jca.13820

Table 1.

Correlation between Tie2 expression and clinical classification in OSCCs.

Clinical classification	Total	Immunostaining Results No. patients		p value^a
Clinical classification	Total	Tie2-negative	Tie2-positive	p value^a
Age at surgery (years)
<60	18	14	4
≧60, <70	20	13	7	0.788^a
≧70	32	25	7
Gender
Male	47	34	13	0.773^b
Female	23	18	5	0.773^b
T-primary tumor
T1	5	3	2	0.051^c
T2	48	33	15
T3	9	8	1
T4	8	8	0
N-regional lymph node
Negative	53	35	18	0.008^b**
Positive	17	17	0	0.008^b**
Vascular invasion
Negative	53	37	16	0.203^c
Positive	17	15	2	0.203^c
Stage
I	3	1	2	0.006**^c
II	49	28	21
III	19	15	4
IV	44	24	20
Histopathologic type
Well	54	38	16	0.175^c
Moderately	13	11	2
Poorly	3	3	0
Tumoral site
Tongue	47	35	12	0.846^c
Gingiva	14	9	5
Buccal mucosa	3	3	0
Soft palate	3	2	1
Oral floor	3	3	0

**p < 0.01.

^aχ² test.

^bFisher's exact test.

^cMann-Whitney U-test.