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. 2016 Apr 5;4:16004. doi: 10.1038/boneres.2016.4

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Copyright © 2016 Sichuan University

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

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Localization of [¹⁸F]-FDG in bone. (a) Whole-body PET/CT image of 6-week-old C57BL/6 male mouse 2 h after [¹⁸F]-FDG administration. (b) [¹⁸F]-FDG uptake in the right hind limb of the mouse from a. (c) Computer rendering of PET/CT image of [¹⁸F]-FDG uptake of the distal femur and proximal tibia of mouse from a. (d) Whole-mount tissue section of 6-week-old C57BL/6 male mouse hind limb with autoradiograph on the right showing [¹⁸F]-FDG uptake in the distal femur and proximal tibia. Arrows denote uptake in the cortical bone compartment. (e) PET/CT image of the spinal column of a 6-week-old C57BL/6 male mouse. Images are representative of five mice. Intensity thresholds map counts per second per voxel.