Table 3. Study population characteristics stratified by any histological abnormalities.
A donor was considered to have any histological abnormalities if he/she had at least 1 abnormality in any of: glomerular sclerosis, interstitial fibrosis and tubular atrophy, mesangial matrix increase, arteriolar hyalinosis, and/or vascular fibrous intimal thickening.
| Characteristics | Donors with any histological abnormalities (n=204) |
Donors without any histological abnormalities (n=106) |
p-value |
|---|---|---|---|
| Age at donation (y), median (IQR) |
48.1 (40.4–55.2) | 45.9 (37.4–53.1) | 0.04 |
| African American, n(%) |
16 (7.8) | 7 (6.6) | 0.7 |
| Female, n(%) | 131 (64.2) | 72 (67.9) | 0.5 |
| Preoperative systolic blood pressure (mmHg), median (IQR) |
124 (110–132) | 118 (110–130) | 0.1 |
| Preoperative eGFR (mL/min/1.73m2), median (IQR) |
96.3 (85.7–107.6) | 99.0 (87.5–105.1) | 0.5 |
| Follow-up time (y), median (IQR) |
6.3 (2.5–8.7) | 6.1 (2.6–8.7) | 0.8 |
| Post-donation eGFR, (mL/min/1.73m2), median (IQR) |
58.6 (50.8–69.0) | 59.8 (52.5–69.4) | 0.1 |
| Number of post- donation eGFR measurements per donor, median (IQR) |
5 (3–8) | 5 (3–9) | 0.2 |