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The mean plasma concentration-time curves of chlorzoxazone after the intravenous administration of 1 mg/kg of chlorzoxazone to control (open triangle) and caderofloxacin-treated (solid square) rats. Caderofloxacin (9 mg/kg) was given via an intragastrical administration twice daily for 14 d. The data are expressed as the mean±SD (n=6). bP<0.05, cP<0.01 vs in the absence of caderofloxacin.
