Table 4. The desired target range of Tac concentration, the predicted daily dosage range and the observed daily dose of Tac in overall (n=231) and CYP3A5^*3/^*3 subjects (n=173). Mean±SD.

Subjects	Desired target range of concentration (ng·mL−1)a	Predicted daily dosage range (mg·d−1)		Observed daily dose (mg·d−1)
		Lower bound	Upper bound
Overall	3–7	1.0±0.4	3.7±1.5	3.4±1.5
CYP3A5*3/*3 genotype	3–7	0.9±0.4	3.2±1.6	3.1±1.5

^aThe desired target range of concentration was set according to the clinical practice in the 3rd Affiliated Hospital of Xiangya Medical Institute, Central South University;