Table 2. Pharmacokinetic parameters of Pue in plasma.

Parameters	Pue-only (po)	Pue+ (+)-C (po)	Pue-only (iv)	Pue+ (+)-C (iv)
AUC0–12 h (mg/L·h)	3.74±1.20	9.29±2.36c	91.04±11.88	91.66±9.61
MRT0–12 h (h)	3.41±0.41	3.18±0.63	1.17±0.38	1.24±0.32
Tmax (h)	0.49±0.29	0.47±0.32	0.05	0.05
Cmax (mg/L)	1.07±0.39	4.19±2.25b	109.61±4.34	117.33±16.61
Fab (%)	2.10±0.39	5.27±0.91c	NA	NA

Note: Data represent mean±SD (n=5). NA, not applicable.

Compared to Pue (po)-only, ^bP\<0.05; ^cP\<0.01.