Table 3. The effect of P-gp/MRP-2 inhibitors on the transport of (+)-C across Caco-2 cell monolayers at 60 min.

Group	Papp (10−7cm/s)
	AP→BL	BL→AP	PDR
(+)-C 300 μmol/L	4.55±0.88	7.97±2.22	1.75
(+)-C 300 μmol/L+10 μmol/L Cyclosporin A	4.14±1.73	2.57±0.31b	0.62
(+)-C 300 μmol/L+50 μmol/L MK-571	9.14±1.13b	7.26±1.25	0.79

Note: Data represent mean±SD (n=3).

Compared with (+)-C -only group, ^bP\<0.05.