Figure 5.
Effects of the pSilence-S and -M treatments on the organ histopathologies in the suckling mice infected with HTNV. The suckling mice were infected with lethal doses of HTNV 76–118 and treated with pSilence-S or pSilence-M at 1 and 3 dpi, respectively. Hematoxylin and eosin (H&E)-stained sections of the lungs, kidneys and brains collected from each experimental group at 8 dpi are shown.