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. 2016 Mar 24;7:11021. doi: 10.1038/ncomms11021

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(a) hnRNPU was knocked down (KD) in mLFs and hFFs using siRNAs. Scr refers to the scramble siRNA and KD1 and 2 refer to different siRNAs used. Gapdh used as loading control. (b) Sox2+mouseRRD and Sox2+human RRD were overexpressed in hnRNPU KD conditions in mLFs and hFFs, respectively. smRNA FISH using Alexa 594 (‘red') probes targeting the Sox2 exon. Sox2 nuclear localization percentages are included. WT, wild type.