Pathways involved in the metabolism of DAG and PA described in this review. DGK, diacylglycerol kinase. DAG, Diacylglycerol; PA, phosphatidic acid; PC, phosphatidylcholine; PIP2, phosphatidylinositol 4,5-bisphosphate; IP3, inositol 1,4,5-trisphosphate; PLD, phospholipase D; PLC, phospholipase C; PI4P, Phosphatidylinositol 4-phosphate; PI, phosphatidylinositol; PKD, protein kinase D; PKC, protein kinase C; ARF GAP, ARF GTPase-activating protein. Solid arrows indicate the metabolic pathway, hollow arrows indicate the downstream effector activated by DAG or IP3.