Table 3.
Neuropsychological functioning. Test scores are expressed as mean, (SD). Percentages of impairment (% impaired) are related to available cut-off scores of normality (≥95 % of the tolerance limit of the normal population distribution); statistically significant differences between patients and healthy controls are shown in bold
| DM1 patients (n = 65) | Controls (n = 26) | |||
|---|---|---|---|---|
| mean corrected scores | % impaired | mean corrected scores | p-value | |
| RAVLT IR | 42 (7.2) | 5.8 | 46.8 (8.4) | .013 |
| RAVLT DR | 9.1 (1.8) | 1.9 | 9.8 (2.5) | .370 |
| Rey Osterrieth Figure (ROCF) Copy | 27.5 (6.5) | 46.9 | 32 (6.5) | .007 |
| Rey Osterrieth Figure (ROCF) IR | 13.8 (6.0) | 32.7 | 19.8 (6.6) | < .001 |
| Rey Osterrieth Figure (ROCF) DR | 13.2 (6.7) | 36.7 | 19.7 (6.4) | < .001 |
| Digit Span | 5.1 (1.1) | 24 | 6.2 (1.2) | .002 |
| Corsi’s Block Test (CBT) | 4 (0.8) | 43.1 | 5 (0.8) | < .001 |
| Trail Making Test A (TMT A) | 55.5 (34.9) | 21.3 | 41 (14.3) | .003 |
| Trail making Test B (TMT B) | 130.5 (60) | 17.4 | 108.3 (47.2) | .072 |
| FAS (phonemic fluency) | 28.4 (9.8) | 25.5 | 44.7 (9.0) | < .001 |
| FAB | 15 (1.4) | 25 | 16.3 (0.6) | < .001 |
| STROOP Time Interference | 32.8 (24.8) | 32.7 | 18.9 (6.4) | < .001 |
| STROOP Error Interference | 3.2 (4.4) | 36.7 | 1 (0.9) | .001 |
| PM47 | 30.8 (36.4) | 18.9 | 30.6 (2.3) | < .001 |
| WCST Categories (Cat) | 3.8 (1.9) | 43.4 | 5.6 (0.8) | < .001 |
| WCST Perseverative Errors (pe) | 5.5 (4.4) | 47.2 | 1.9 (1.2) | < .001 |