Table 3.
ROC curve for predicting diabetes and cutoff points for maximum sum of sensitivity and specificity
| ROC (95 % CI) | Cut point | Sensitivity (%) | Specificity (%) | ROC (95 % CI)a | |
|---|---|---|---|---|---|
| LDL-C (mmol/L) | 0.632 (0.608–0.655) | 1.20 | 0.60 | 0.61 | 0.648 (0.608–0.687) |
| HDL-C (mmol/L) | 0.603 (0.579–0.627) | 1.18 | 0.65 | 0.53 | 0.632 (0.589–0.674) |
| TG (mmol/L) | 0.659 (0.637–0.683) | 1.23 | 0.58 | 0.65 | 0.669 (0.629–0.708) |
| TC (mmol/L) | 0.621 (0.597–0.646) | 1.19 | 0.53 | 0.66 | 0.626 (0.585–0.668) |
| Non-HDL-C (mmol/L) | 0.656 (0.634–0.679) | 1.23 | 0.61 | 0.62 | 0.673 (0.635–0.712) |
| TG/HDL-C | 0.666 (0.643–0.688) | 1.24 | 0.87 | 0.37 | 0.682 (0.644–0.720) |
| TC/HDL-C | 0.684 (0.663–0.705) | 1.30 | 0.77 | 0.53 | 0.717 (0.680–0.754) |
HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, Non-HDL-C non-high-density lipoprotein cholesterol, TC total cholesterol, TG, triglycerides. Cut points are presented as mmol/L
TC/HDL-C was a better predictor than LDL-C (comparing ROC: P < 0.001), HDL-C (P < 0.001), TG (P = 0.012), TC (P < 0.001), non-HDL-C (P = 0.001), and TG/HDL-C (P = 0.03)
aFurther excluded individuals with hypertension