Figure 3.

Effects of NM on lung macrophage expression of M1 and M2 genes. Lung macrophages, isolated 1, 3, 7, and 28 days after exposure of rats to PBS CTL or NM, were analyzed for gene expression by RT-PCR. Data were normalized relative to glyceraldehyde 3-phosphate dehydrogenase and presented as fold change relative to CTL. Error bars, mean ± SE (n = 3–5 rats). *Significantly different (P ≤ 0.05) from CTL. ApoE, apolipoprotein E; COX, cyclooxygenase; CTGF, connective tissue growth factor; MMP, matrix metalloproteinase; PTX, pentraxin.