Table 1.
SNP Sets | GWAS Hits (n) | 10% FDR |
20% FDR |
||||
---|---|---|---|---|---|---|---|
cis eQTLs (n) | trans eQTLs (n) | Enrichment fold | cis eQTLs (n) | trans eQTLs (n) | Enrichment fold | ||
All diseases | 11,598 | 129 | 0 | 9.2† | 171 | 0 | 7.5† |
Airway diseases | 538 | 6 | 0 | 9.2‡ | 6 | 4 | 9.5‡ |
Definition of abbreviations: eQTL, expressional quantitative trait locus; FDR, false discovery rate; GWAS, genome-wide association study; SNP, single-nucleotide polymorphism.
At 10 and 20% FDR, we detected 660 and 1,066 small airway eQTLs, respectively.
Significant at the <0.005 level based on resampling test.
Not statistically significant based on resampling-based test.