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. 2016 Feb;54(2):177–187. doi: 10.1165/rcmb.2014-0381OC

Table 1.

Intersecting National Human Genome Research Institute Genome-Wide Association Studies Results with Small Airway Expressional Quantitative Trait Loci*

SNP Sets GWAS Hits (n) 10% FDR
20% FDR
cis eQTLs (n) trans eQTLs (n) Enrichment fold cis eQTLs (n) trans eQTLs (n) Enrichment fold
All diseases 11,598 129 0 9.2 171 0 7.5
Airway diseases 538 6 0 9.2 6 4 9.5

Definition of abbreviations: eQTL, expressional quantitative trait locus; FDR, false discovery rate; GWAS, genome-wide association study; SNP, single-nucleotide polymorphism.

*

At 10 and 20% FDR, we detected 660 and 1,066 small airway eQTLs, respectively.

Significant at the <0.005 level based on resampling test.

Not statistically significant based on resampling-based test.