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. 2016 Feb;54(2):222–230. doi: 10.1165/rcmb.2014-0461OC

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Figure 3. — Models of interstitial lung fibrosis. Chronic bleomycin or transforming growth factor (TGF) β1 adenovirus efficiently induced pulmonary fibrosis. (A) Whole-mount images showing atelectasis and scarring in bleomycin-treated lungs compared with saline-treated controls. CaL, caudal lobe; CrL, cranial lobe; LL, left lobe. (B and C) Picrosirius-red staining revealed collagen deposition, cell infiltration, and honeycombing after bleomycin (B) or transforming growth factor-β1 (TGF-β1) (C) treatment. Scale bar = 1 mm (A), 100 μm (B and C).