Table 1.
Patient Demographics
| Patient* | Age (yr) | Sex | Genotype G551D | BMI (kg/m2) | FEV1(L), Percentage Predicted | Sputum Microbiology |
|---|---|---|---|---|---|---|
| 1 | 23 | F | ΔF508 | 29.7 | 3.08 (87%) | PA |
| 2 | 25 | F | ΔF508 | 25.5 | 2.71 (80%) | PA, MSSA |
| 3 | 23 | F | ΔF508 | 21.8 | 2.74 (88%) | SA, AF |
| 4 | 30 | F | ΔF508 | 20.4 | 1.05 (38%) | PA |
| 5 | 27 | F | ΔF508 | 20.2 | 1.71 (58%) | PA, MRSA |
| 6 | 22 | F | 3659delC | 18.4 | 1.22 (38%) | PA, CA, AF |
| 7 | 33 | F | ΔF508 | 17.1 | 2.57 (89%) | PA |
| 8 | 57 | F | P67L | 19.5 | 0.94 (39%) | MSSA, CA |
| 9 | 35 | F | ΔF508 | 20.6 | 2.17 (78%) | PA |
| 10 | 29 | M | G551D | 23.2 | 4.16 (106%) | PA |
| 11 | 30 | M | ΔF508 | 23.4 | 1.60 (39%) | MSSA, BM |
| 12 | 33 | M | R117H | 22.1 | 2.71 (71%) | BC, CA |
Definition of abbreviations: AF, Aspergillus fumigatus; BC, Burkholderia cepacia; BM, Burkholderia multivorans; BMI, body mass index; CA, Candida albicans; CF, cystic fibrosis; F, female; FEV1, forced expiratory volume in 1 sec; M, male; MSSA, methicillin-sensitive Staphylococcus aureus; MRSA, methicillin-resistant Staphyloccus aureus; PA, Pseudomonas aeruginosa; SA, Staphyloccus aureus.
*
All patients received routine CF care at the adult CF clinic at St. Vincent’s Hospital, Dublin, Ireland, and this study was approved by the St. Vincent’s Hospital’s Institutional Review Board.