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. Author manuscript; available in PMC: 2016 Apr 5.
Published in final edited form as: Gene Ther. 2008 Apr 10;15(18):1257–1270. doi: 10.1038/gt.2008.58

Figure 4.

Figure 4

Role of the Ras signalling pathway in reovirus-induced cytotoxicity. Mel-624, Mel-888 and Skmel-28 cells that had been exposed to 10 µm SB202190 (a), U0126 (b) or LY294002 (c) were either left untreated or infected with reovirus at a multiplicity of infection (MOI) approximately equal to the IC50. Cell survival was determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay at 96 h. Data are representative of at least three independent experiments. Error bars represent s.e.m.