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. Author manuscript; available in PMC: 2016 Apr 5.
Published in final edited form as: J Biol Chem. 2007 Dec 17;283(8):5046–5057. doi: 10.1074/jbc.M709231200

FIGURE 3. S100A1−/−muscle fibers exhibit decreased peak amplitude of the Fluo-4 Ca2+transient.

FIGURE 3

A, average transient responses to single AP stimulation from similar assay to Fig. 2A, performed with non-ratiometric Fluo-4 AM loaded fibers and assayed with high speed confocal line scan microscopy (50 μs/line) for increased temporal resolution. Data presented as ΔF/Fo. B, bar plot summarizing differences in peak amplitude of fluorescent transient. WT =5.78 ± 0.38, n =26; KO =3.95 ±0.27, n =25. *, data were significantly different at p = 0.0003.