Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Ionic mechanisms underlying electrotonically-triggered EAD formation. From top to bottom: time course of the action potential, ICaL, ICaL activation gate, calcium release current from the sarcoplasmic reticulum, INa and IKr for human ventricle cardiomyocytes representative of NZ, BZ and ICZ under varying degrees of repolarization reserve (0, 30 and 50% IKr reduction corresponding to short dash, long dash and continuous lines). Stimulation protocol and ischemic conditions as in Fig. 7.
