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. 2016 Feb 27;6(4):251–263. doi: 10.1002/2211-5463.12027

Figure 8.

Figure 8

Down‐regulation of CUL5 protein by hsa‐miR‐148a. Western Blot analyses of CUL5 levels. (A) pSG5‐miR‐148a and the empty control (pSG5) were transfected in HEK293T cells. miR‐148a overexpression down‐regulated the CUL5 level significantly (*P = 0.0003). (B) CUL5 is up‐regulated in NK/T‐cell lines (SNK6 and SNT16) compared to nontransformed CD56+/CD3+‐primary cells (***P = 0.0002, *P = 0.016 respectively). (C, D) Western Blot quantification of at least three independent experiments. Error bars show SD.