Table 2.
Clinical coarse.
| pre PEA | post PEA | Hospitalization | Exacerbation | BPA 1st | BPA 2nd | BPA 3rd | BPA 4th | BPA 5th | 4 month | 15 month | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| WHO-FC | Ⅲ | Ⅰ | Ⅲ | Ⅳ | Ⅲ | Ⅲ | Ⅲ | Ⅲ | Ⅱ | Ⅰ | Ⅰ |
| O2 (L)/DOB(γ) | room air/0 | room air/0 | room air/0 | 5.0/2.0 | 5.0/2.0 | 5.0/2.0 | 4.0/0 | 4.0/0 | 4.0/0 | room air/0 | room air/0 |
| BP (mmHg) | 109/73 | 127/81 | 118/75 | 105/72 | 110/68 | 120/68 | 120/68 | 122/68 | 127/69 | 124/76 | 105/70 |
| HR (bpm) | 86 | 101 | 88 | 106 | 120 | 112 | 102 | 95 | 98 | 98 | 88 |
| BNP (pg/ml) | 67 | 18 | 100 | 196 | 96 | 92 | 87 | 18 | 28 | 6 | 14 |
| TRPG (mmHg) | 58 | 24 | 95 | 120 | 100 | 97 | 60 | 42 | 47 | 30 | 22 |
| RAP (mmHg) | 0 | 0 | 2 | 9 | 6 | 3 | 3 | 7 | 1 | 1 | 1 |
| PA (mPAP) (mmHg) | 96/40 (56) | 30/14 (20) | 96/37 (57) | 110/37 (67) | 108/40 (65) | 104/38 (63) | 79/32 (49) | 82/35 (48) | 56/24 (35) | 45/20 (28) | 34/13 (20) |
| PCW (mmHg) | 10 | 2 | 6 | 6 | 12 | 6 | 6 | 12 | 4 | 12 | 6 |
| PVR (wood.units) | 11.3 | 3.8 | 12.3 | 11.5 | 9 | 11 | 7.8 | 5.9 | 5.3 | 2.5 | 2.5 |
| SvO2 (%) | 69 | 70 | 67 | 58 | 76 | 74 | 78 | 79 | 83 | 72 | 75 |
| CO/CI (L/m, L/m/m2) | 4.1/2.3 | 4.8/2.9 | 4.2/2.4 | 5.3/3.1 | 5.8/3.4 | 5.6/3.4 | 6.7/4.0 | 6.6/4.0 | 7.9/4.8 | 6.5/3.9 | 5.9/3.5 |
| MRI: RVEF (%) | 11 | 23 | 31 | ||||||||
| MRI: LVEF (%) | 40 | 46 | 50 | ||||||||
| pO2 (torr) | 58 | 80 | 80 | 66 | 88 | 88 | 124 | 85 | 117 | 110 | 85 |
| pCO2 (torr) | 30 | 37 | 37 | 36 | 37 | 40 | 33 | 39 | 37 | 40 | 39 |
| DLCO (%) | 69 | 45 | 64 | 56 | 57 | 57 | 60 | 55 | 60 | 64 | |
| VC (%) | 104 | 77 | 100 | 82 | 86 | 90 | 93 | 96 | 98 | 100 | |
| FEV1.0 (%) | 78 | 99 | 82 | 82 | 83 | 80 | 84 | 82 | 83 | 87 | |
| peak VO2 (ml/min/kg) | 26.4 | ||||||||||
| AT (ml/min/kg) | 7.8 | ||||||||||
| 6MWD (m) | 260 | 370 | 560 | 570 | |||||||
| Amount of Gd (ml) | 90 | 50 | 59 | 40 | 45 |
WHO FC: World Health Organization Function Class, O2: Oxygen, DOB: Dobutamine Hydrochloride, BP: Blood Pressure, HR: Heart Rate, TRPG: Tricuspid Regurgitation Pressure Gradient, mPAP: mean Pulomonary Artery Pressure, PCW: Pulmonary Capillary Wedge Pressure, PVR: Pulmonary Vascular Resistance, SvO2: Venous Oxygen Saturation, CO: Cardiac Output, CI: Cardiac Index, MRI: Magnetic Resonance Imaging, RVEF: Right Ventricular Ejection Fraction, LVEF: Left Ventricular Ejection Fraction, pO2: Partial Pressure of Oxygen, pCO2: Partial Pressure of Carbon Dioxide, DLCO: Diffuse Capacity of Carbon Monoxide, FEV1.0: Forced Expiratory Volume % one second, Peak VO2: Peak Oxygen Uptake, AT: Anaerobic Threshold, 6MWD: Six Minutes Walk Distance, Gd: Gadolinium contrast medium.