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. Author manuscript; available in PMC: 2016 Apr 5.
Published in final edited form as: J Immunol. 2014 Jul 25;193(5):2118–2126. doi: 10.4049/jimmunol.1400056

Figure 7. Functional activity of 21-OHspecific CD8+ T cells.

Figure 7

(A) ELISA with granzyme B specific antibody from supernatant of the HLA-A2 restricted 21-OH342-350 specific T cell clone co-cultured with the HLA-A2+ 21-OH expressing tumor cell line NCI H295 in the presence of absence of the HLA-A2 blocking antibody BB7.2. Positive control with NCI H295 cells pulsed with peptide 21-OH342-350 is shown. (B) Increased expression of CD107 on the surface of the HLA-A2 restricted 21-OH342-350 specific T cell clone co-cultured with the HLA-A2+ 21-OH expressing tumor cell line NCI H295 in the presence of absence of the HLA-A2 blocking antibody BB7.2. Positive control with NCI H295 cells pulsed with peptide 21-OH342-350 is shown. The results are representative of two experiments.