Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Mar 29;9:1801–1812. doi: 10.2147/OTT.S96535

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 Zhang et al. This work is published and licensed by Dove Medical Press Limited

The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

PMC Copyright notice

Effect of Twist2 on tumor growth in vivo.

Notes: (A) 786-0 cells transfected with shNC or shTwist2 were subcutaneously injected in athymic nude mice. Tumor growth was shown 46 days after injection (n=6). (B) Tumor weight in shTwist2-treated mice was significantly decreased compared with that in control and shNC mice. (C) shTwist2 decreased tumor growth in mice compared with that in control and shNC mice. (D, E) Expression of Twist2 and Ki67 was detected by Western blot at 46 days after shNC or shTwist2 injection. Scale bars: 10 mm. *P<0.001 compared with shNC.

Abbreviations: shNC, recombinant lentivirus pLKO.1-EGFP-scramble shRNA; NC, black pWPXL; shTwist2, recombinant lentivirus pLKO.1-EGFP-Twist2.