Table 2. Adjusted associations between patient characteristics and receipt of TL (vs. CTRT).
| Characteristic | Adjusted Odds Ratio (95% CI) | ||||
|---|---|---|---|---|---|
|
| |||||
| Age at diagnosis | |||||
| 66-69 | Ref | ||||
| 70-74 | 0.88 (0.59 - 1.31) | ||||
| 75-59 | 1.09 (0.69 - 1.72) | ||||
| 80-84 | 1.06 (0.59 - 1.89) | ||||
| 85+ | 1.14 (0.5 - 2.6) | ||||
|
| |||||
| Sex | |||||
| Male | Ref | ||||
| Female | 0.99 (0.66 - 1.47) | ||||
|
| |||||
| Race | |||||
| White | Ref | ||||
| Black | 1.13 (0.66 - 1.94) | ||||
| Other | 0.67 (0.35 - 1.31) | ||||
|
| |||||
| Census tract median income | |||||
| 1st quartile | Ref | ||||
| 2nd quartile | 0.8 (0.5 - 1.29) | ||||
| 3rd quartile | 0.74 (0.45 - 1.22) | ||||
| 4th quartile | 0.8 (0.46 - 1.38) | ||||
|
| |||||
| Urban-rural residence | |||||
| Metro | Ref | ||||
| Non-metropolitan | 1.25 (0.77 - 2.06) | ||||
|
| |||||
| Region | |||||
| Northeast | Ref | ||||
| South | 1.19 (0.7 - 2.02) | ||||
| Midwest | 1.31 (0.74 - 2.32) | ||||
| West | 1.24 (0.8 - 1.92) | ||||
|
| |||||
| Married | |||||
| Yes | Ref | ||||
| No | 1.01 (0.72 - 1.44) | ||||
| Unknown | 1.48 (0.67 - 3.3) | ||||
|
| |||||
| Site | |||||
| Glottis | Ref | ||||
| Supraglottis | 0.61 (0.41 - 0.91) | ||||
| Other | 1.68 (1.05 - 2.7) | ||||
|
| |||||
| Clinical T-stage | |||||
| T1/T2 | Ref | ||||
| T3 | 2.47 (1.42 - 4.3) | ||||
| T4 | 5.62 (3.26 - 9.67) | ||||
|
| |||||
| Lymph node involvement | |||||
| Negative | Ref | ||||
| Positive | 1.18 (0.81 - 1.73) | ||||
| Unknown | 0.64 (0.28 - 1.46) | ||||
|
| |||||
| Charlson comorbidity score | |||||
| 0 | Ref | ||||
| 1 | 1.04 (0.71 - 1.53) | ||||
| 2+ | 1.37 (0.88 - 2.13) | ||||
|
| |||||
| Year of diagnosis | 0.81 (0.75 - 0.86) | ||||
Abbreviations: TL, total laryngectomy; CTRT, chemoradiation; CI, confidence interval
Notes: Other site includes subglottis, overlapping tumors and cancer of the larynx not otherwise specified.