Table 2. Combination treatment with 17-AAG and CDDP or DTIC.

		Combination index
	NQO1	17-AAG + CDDP			17-AAG + DTIC
		IC50	IC75	IC90	IC50	IC75	IC90
SK-MEL-31	−	2.184	1.765	1.444	1.285	1.258	1.291
GAK	−	0.808	0.664	0.593	0.900	0.961	1.028
MeWo	+	0.686	0.447	0.306	0.756	0.955	1.211
SK-MEL-2	+	0.732	0.625	0.534	0.494	1.248	4.205
G-361	+	1.176	0.844	0.666	1.488	2.702	5.082
A7 (KEAP1 MT)	++	1.275	1.022	0.873	0.370	0.608	1.172