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. 2016 Apr 5;10(4):e0004502. doi: 10.1371/journal.pntd.0004502

Table 3. Reaction type and nerve involvement in study participants.

Participants with new T1R Ciclosporin Prednisolone P value
(n = 35) (n = 38)
Reaction type Skin only 4 8 0.541
Skin and nerves 28 27
Nerve only 3 3
Facial patches 29 25 0.164
Peripheral Oedema 30 28 0.414
Reported NFI at baseline None 3 9 0.039
New 20 10
Old 4 4
Mixed old and new 8 15
Mean number of enlarged nerves per patient 9 8.5 0.306
Mean number of tender nerves per patient 4.7 3.6 0.168

Type 1 reaction occurring in both skin and nerves was present in 76% of participants, whilst 16% had reaction affecting skin only and 8% nerves only. 74% of patients had inflamed facial patches and 80% had peripheral oedema on examination.