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. 2016 Apr 5;11(4):e0153038. doi: 10.1371/journal.pone.0153038

Fig 1. Infection parameters of Swiss mice infected with 50,000 trypomastigotes of the Y strain of T. cruzi.

Fig 1

(A) The peak of parasitemia was at the 9th d.a.i. (B) The mortality rate until the 20th d.a.i. was significantly high, with death of approximately 50% of the animals treated with benznidazole. (C) The body mass of the chronic-phase infected group decreased compared with the control group but increased compared with the acute-phase infected group. (D) Colon length increased in the chronic-phase infected group compared with the control group of paired animals and with the acute-phase infected group. (E) ELISA of anti-T. cruzi total IgG was negative in the acute-phase infected group and positive in the chronic-phase infected group. Values represent the means ± SEM. *p = 0.023, **p = 0.001, N = 10 for each experimental and control group. The results represent two independent experiments. Black: infected groups; white: control groups.