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. 2016 Apr 5;11(4):e0153015. doi: 10.1371/journal.pone.0153015

Fig 8. Naringenin increases Nrf2 and HO-1 mRNA expression.

Fig 8

(a-b) Mice received naringenin (50 mg/kg, po) treatment 1 h before ipl injection of 30 μg KO2. Paw skin samples were collected 3 h after ipl KO2 injection for (a) Nrf2, and (b) HO-1 mRNA expression analysis by RT-qPCR. β-actin was a reference gene to normalize mRNA expression data. Results are mean ± SEM of 6 mice per group per experiment, and are representative of 2 independent experiments. *p< 0.05 vs. saline group, #p< 0.05 vs. KO2 group. One-way ANOVA followed Tukey’s post hoc.