Table 3. Comparison between subjects with human adenovirus (HAdV) species B and C, according to demographic, clinical, and laboratory variablesa.
| Characteristic | HAdV-B species N = 7 | HAdV-C species N = 37 | P value for comparison |
|---|---|---|---|
| n/N (%) | n/N (%) | ||
| Demographic and clinical presentation | |||
| Males (%) | 4/7 (57.1) | 19/36 (52.8) | 0.99 |
| Mean age ± SD, yrs | 3.0 ± 1.9 | 2.8 ± 2.4 | 0.82 |
| Presence of fever” (%) | 5/5 (100.0) | 34/36 (94.4) | 0.99 |
| High-grade fever° (%) | 5/5 (100.0) | 26/36 (72.2) | 0.31 |
| Respiratory rate, breaths/min | 39.2 ± 8.5 | 34.9 ± 10.7 | 0.23 |
| SpO2 in room air, mean % ± SD | 96.6 ± 3.7 | 97.9 ± 1.8 | 0.61 |
| Clinical findings | |||
| Cough | 4/7 (57.1) | 25/37 (67.6) | 0.67 |
| Rhonchi | 0/7 (0.0) | 0/37 (0.0) | - |
| Rales | 3/7 (42.9) | 11/37 (29.7) | 0.66 |
| Wheezes | 0/7 (0.0) | 0/37 (0.0) | - |
| Diagnosis | |||
| Upper respiratory tract infection | 3/7 (42.9) | 26/37 (70.3) | |
| Lower respiratory tract infection | 4/7 (57.1) | 11/37 (29.7) | 0.21 |
| Clinical outcome | |||
| Hospitalization rate, no.(%) | 3/7 (42.9) | 9/37 (24.3) | 0.37 |
| Drug use, no. (%) | |||
| Antibiotics | 4/7 (57.1) | 34/37 (91.9) | 0.04 |
| Antipyretics | 3/4 (75.0) | 27/29 (93.1) | 0.33 |
| Aerosol therapy | 1/4 (25.0) | 10/29 (34.5) | 0.99 |
| Absence from child care attendance, mean days ± SD | 4.5 ± 0.7 | 9.6 ± 7.8 | 0.37 |
| Similar illness within the households | 1/5 (20.0) | 13/30 (43.3) | 0.63 |
| Laboratory data | |||
| White blood cell count (cells/μL) | 9,565 ± 3,211 | 17,244 ±7,737 | 0.04 |
| Neutrophils, % | 57.6 ± 6.8 | 61.1 ± 17.8 | 0.99 |
| CRP, μg/dL | 5.9 ± 7.1 | 27.4 ± 69.7 | 0.87 |
CRP, C reactive protein; SD, standard deviation; SpO2, peripheral oxygen saturation.”38.0°C or more any time during the illness (before or at enrolment, or during follow-up); °39.0°C or more any time during the illness (before or at enrollment or during follow-up).
aData were extracted from datasets of different studies that collected different information; therefore, the denominators vary across characteristics. However, when not indicated the reported number refers to the whole enrolled sample.